Acura MDX Vs. Lexus RX 350 – Which Is Better?
2026 Acura MDX vs. Lexus RX 350 at a Glance
- The Acura MDX seats seven across three rows, while the two-row Lexus RX 350 only accommodates five.
- Potent V-6 power motivates the MDX compared to a less enthusiastic four-cylinder in the RX 350.
- Both SUVs are known for their strong reliability.
- With 71.4 cubic feet of cargo space behind the front row, the MDX has significantly more room for your gear than its competitor.
- Despite being longer than the Lexus, the Acura MDX is highly maneuverable.
Is a Lexus RX 350 Better Than an Acura MDX?
When it comes to unique style and road presence, the Acura MDX vs. Lexus RX 350 is a compelling midsize SUV comparison. Though the team here at Muller's Woodfield Acura answers the posed question with a resounding no, we'll let you draw your own conclusion. Shoppers can determine whether they value the Acura MDX's three-row layout and more potent V-6 power or the Lexus RX 350's five-seat cabin and smaller four-cylinder. Read on to discover which model can best serve as your daily driving companion.
Acura MDX vs. Lexus RX 350 Seating
The 2026 MDX offers three rows and seating for seven, whereas the RX 350 only accommodates five occupants across two rows.
With seating for seven, the 2026 MDX is built for family life. Its three spacious rows give everyone room to spread out, helping reduce the stress of everyday life. On the other hand, the RX 350 has a more compact cabin with space for five occupants. While one configuration isn't inherently better than the other, the MDX is better positioned to accommodate larger and growing families.
2026 Acura MDX vs. Lexus RX 350 Powertrain Specs
The Acura MDX is powered by either a naturally aspirated or a turbocharged V-6 engine, whereas the RX 350 opts for a less potent turbocharged four-cylinder powertrain.
The 2026 Acura MDX packs a mighty punch with two different V-6 engine offerings. The standard powertrain is a 3.5-liter V-6 with 290 horsepower and 267 pound-feet of torque, while the performance-oriented Acura MDX Type S Advance packs a 3.0-liter turbocharged V-6 under its hood, increasing output to 355 horsepower and 354 pound-feet of torque.
The Lexus RX 350 engine lags behind with a single 275-horsepower 2.4-liter turbo four-cylinder engine. Its 317 pound-feet of torque is admirable, but its eight-speed automatic transmission isn't as smooth as the Acura SUV's 10-speed automatic unit. While both have paddle shifters, the MDX adds in rev-matching downshifts with its available turbo V-6.
Acura MDX vs. Lexus RX 350 Reliability
Both SUVs are known for their reliability, with high ratings from third-party experts.
Admittedly, both SUVs are heralded as reliable automobiles, with the 2026 Acura MDX earning high ratings from experts like Kelley Blue Book® and Consumer Reports. Of course, the RX 350 scores high marks, too.
Compare Lexus RX 350 and Acura MDX Specs Side by Side
| 2026 Acura MDX | 2026 Lexus RX 350 | |
| Engine |
|
2.4L turbo 4-cyl |
| Horsepower |
|
275 |
| Torque |
|
317 lb-ft |
| Transmission |
|
8-speed auto |
| Drivetrain | FWD or SH-AWD | FWD or AWD |
| Max. EPA-Est. MPG (City / Hwy) | 19 / 26 / 221 | 22 / 29 / 252 |
| Fuel Tank | 18.5 gal | 17.8 gal |
| Max. Towing Capacity | 5,000 lbs3 | 3,500 lbs4 |
| Passenger Seating | 7 | 5 |
| Cargo Volume (Behind 3rd / 2nd / 1st Row) | 16.3 / 39.1 / 71.4 cu ft | - / 29.6 / 46.2 cu ft |
Acura MDX vs. Lexus RX 350: How Do Their Cabins Measure Up?
While both the Acura MDX and Lexus RX 350 are positioned as midsize luxury SUVs, the former pulls ahead thanks to its robust feature set with more advanced technologies and premium creature comforts.
Every Acura MDX is equipped with heated, 12- or 16-way power-adjustable front sport seats and a leather-wrapped steering wheel. Tri-zone automatic climate control, a wireless charging pad, and multiple USB ports come standard to keep you and your passengers comfortable and connected on the go. There's plenty more to discover throughout the model's trim ladder.
While the RX 350 also comes fitted with heated front seats, a leather-wrapped steering wheel, a wireless charging pad, and multi-zone climate control, the front seats only offer eight- or 10-way power adjustability, depending on the trim. Additionally, where all but the entry-level MDX give some form of premium Milano leather, only two RX 350 models come with genuine leather – the rest have synthetic NuLuxe upholstery.
Experience Luxury and Adventure In a 2026 Acura MDX
If you're looking to spruce up your daily commute, we think the 2026 Acura MDX is the clear winner. You can also browse new Acura inventory in Hoffman Estates, IL, to see other high-end automobiles from the automaker.
While you're here, we have plenty of Acura model research and comparisons to help motorists at any stage of their automotive journey learn more about Acura models, such as the RDX and Integra.
Speaking of the RDX, we also compared that to its closest Lexus rival. See how two small luxury crossovers stack up to one another in our Acura RDX vs. Lexus NX 350 showdown.
Muller's Woodfield Acura aims to be drivers' preferred Acura dealer in Illinois, so feel free to stop by if you're in the area. We look forward to assisting you.
Frequently Asked Questions
Which Lexus model is equivalent to the Acura MDX?
While the Lexus RX 350 closely compares with the Acura MDX, the Lexus GX and Lexus LX have V-6 engines and three rows of seating. However, both of these models are priced much higher than the Acura MDX, with only a marginal difference in horsepower and torque. That said, the Acura MDX offers better value for performance and capability.
Is the Acura MDX bigger than the Lexus RX?
Yes, when comparing the Acura MDX versus Lexus RX 350 dimensions, the Acura SUV is longer, wider, and more spacious than the Lexus RX 350. The Acura model also provides three rows of seating, while the Lexus SUV has only two. Drivers with extensive cargo hauling needs will love the Acura MDX's 71.4 cubic feet of load space behind the front row.
Which model offers better fuel efficiency: the MDX or RX 350?
Fuel efficiency is similar for the 2026 Acura MDX and the 2026 Lexus RX 350, though the Lexus model expectedly has slightly higher ratings due to its smaller stature and engine. However, the Acura MDX has a larger fuel tank, so the frequency of trips to the pump likely balances out between these two midsize luxury SUVs. Plus, the MDX provides more strength.
Does Acura or Lexus hold value better?
Acura models tend to hold their value well, especially those like the MDX, which offers strong performance and premium amenities. Competitive pricing and long-term reliability help the MDX's appeal on the used market, too. While Lexus is often praised for resale strength, Acura's balance of capability, luxury, and accessible entry points allow their automobiles to also retain their value over time.
Continue Your Acura Research
| Acura MDX Model Year Comparisons | Acura MDX vs. Honda Pilot | Acura MDX vs. Kia Telluride |
| Acura MDX vs. Toyota Highlander | Acura RDX vs. Lexus NX 350 | Acura RDX Trim Packages |
1Based on 2026 EPA mileage ratings. Use for comparison purposes only. Your actual mileage will vary, depending on how you drive and maintain your vehicle, driving conditions, and other factors.
2EPA-estimated MPG ratings. Use for comparison purposes only. Your mileage will vary for many reasons, including your vehicle’s condition and how/where you drive. See www.fueleconomy.gov.
3Towing requires the addition of the Acura accessory trailer hitch and hitch ball. Please see your Acura dealer for details. Added cargo weight in the vehicle may reduce max towing capacity, see Owners Guide for details.
4Before towing, confirm your vehicle and trailer are compatible, hooked up properly and you have any necessary additional equipment. If gross trailer weight is above 5,000 lb (2,268 kg), it is necessary to use a weight-distributing hitch with sufficient capacity. Do not exceed any Weight Ratings and follow all instructions and cautions from your trailer-hitch manufacturer and vehicle Owner's Manual. The maximum amount you can tow depends on the total weight of any cargo, occupants and available equipment. See Owner's Manual for limitations.